Buy Celexa Online Without Prescription
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Celexa is used for treating depression. Celexa is a selective serotonin reuptake inhibitor. It works by restoring the balance of serotonin, a natural substance in the brain, which helps to improve certain mood problems.
Where to Find the Perfect Anti-depressant?
According to various sources, now from 4 to 18% of all people suffer from depression in their lifetime. The serious impact of depressive disorders is felt at both the individual and societal level. About 4% of the population suffer from panic disorders.
Celexa (Citalopram), which is the selective serotonin reuptake inhibitor. In the treatment of depressive episodes and anxiety disorders drug exerts its clinical efficacy since the first week of use. The Range of Application
The range of application of SSRI antidepressants are not limited only to depressive syndrome. This group is also effective in the treatment of obsessive - compulsive disorder and panic attacks. Various scientists have shown interesting data on the treatment of compulsive shopping, gambling drug citalopram. SSRIs according to the described in the report - are safer in overdose, have low behavioral toxicity (which determines the possibility of their use in the period of active work), do not cause "withdrawal syndrome" in the case of abrupt discontinuation of therapy, more suitable for long-term (preventive) therapy as well as the treatment of the elderly and somatic debilitated patients.
A significant advantage is its Celexa (Citalopram) smaller than that of other antidepressants potential for drug interactions. This is explained by its lower than the intensity of other SSRIs binding to plasma proteins and inhibition of liver isoenzyme cytochrome P-450. That is Celexa not affect the pharmacokinetics of drugs in any combination of concurrent therapy. Systemic bioavailability Celexa (Citalopram) the drug is 80%. Celexa easy (outside the context of a meal) and fast (after 2 - 4 hours) reaches maximum concentration in biological fluids, and it provides the active substance lipotropic light penetration through the blood-brain barrier. Average compared to other SSRIs long half-life of the active substance - 30 - 33 hours (versus 15 hours for fluvoxamine and 4 - 6 days for fluoxetine) can receive guaranteed Celexa once a day. The equilibrium concentration of citalopram in the blood plasma is reached, regardless of the age of the patient rather quickly - by the end of the first week of therapy, it probably causes more early than some other SSRIs appearance of therapeutic effect. Simplicity drug regimens Celexa (Citalopram) - starting dose (20 mg) is also the optimal therapeutic dose, and that avoids patient therapy mode violations and hence promotes the clinical onset of the desired effect. Celexa in the Treatment of Obsessive - Phobic Disorders
Citalopram studies conducted on the basis of the Scientific Center of Mental Health. The sample consisted of 30 patients with panic disorder (18 women, 12 men), mean age 28 years, disease duration 1-20 years (mean 6.9). These studies indicated the effectiveness of the drug in this group. First of all, there is a pronounced anti-panic activity and even, parallel reduction of cognitive and somatic anxiety components. Furthermore, it was found that Celexa has a favorable tolerability profile with minimal side effects. In addition to applying Celexa in patients with panic disorder, the drug's effectiveness has been proven in obsessive - compulsive disorders such as disorder (contrast obsessions, obsessive doubts, take possession of the submission, "ruminations"), movement disorders (multiple rituals, doubts about the implementation of the motion, motor stereotypies).
The studies found that the crucial factor in determining the strategy to overcome drug Celexa resistance, is to analyze the structure of comorbidity of obsessive-phobic symptom with the main manifestations of endogenous process - positive and negative disorders. As a result, it was concluded that Celexa is the only drug whose mechanism of action corresponds exactly to the name of the group of SSRIs (selective serotonin reuptake inhibitor), it does not interact with other neurotransmitter systems, and acts selectively on 5HT2 receptors. This leads to the fact that the side effects are better predictable set of smaller and more diseased komplaenten. Antidepressant Celexa (Citalopram)
Since the beginning of its clinical study in 1976, she went through numerous clinical trials and has been officially registered in more than 70 countries around the world. Citalopram is a selective serotonin reuptake inhibitor, developed by Lundbeck. This is the only drug with the possibility of parenteral administration. It may be noted some of the pharmacological action of Citalopram:
Discussion
For the elderly ideal antidepressant in addition to efficiency should have a minimal number of side effects, safety profile of interactions with other medication and alcohol and received 1 per day. Furthermore, it is desirable that the drug was not active metabolites. Celexa meets all these criteria. A potent inhibitor of the reuptake of serotonin and the most selective of all SSRI antidepressant that is effective, equal to TCAs and other SSRIs. Citalopram also has a beneficial effect on behavioral disorders in elderly patients, including agitation. Its half-life period of 33 hours (slightly higher in the elderly), that allows antidepressant assign 1 time per day. The metabolites of citalopram does not affect the action of the drug.
Side effects are usually mild and citalopram decrease in severity for several weeks of treatment. The most common side effect of antidepressants - nausea, headache, tremor, dry mouth, and abnormal ejaculation. Citalopram (Celexa) has a low potential for interaction with alcohol, as well as with the majority of drugs, including beta blockers, neuroleptics, lithium, tricyclic antidepressants. Unlike tricyclic antidepressants, citalopram does not cause anticholinergic side effects, orthostatic hypotension, drowsiness during the day, is not associated with cardiotoxicity, adverse effects on cognitive and psychomotor functions. With an overdose of citalopram is safe within a wide range, but, like other SSRIs, it should not be used in parallel with the RIMA. Of course, further research is needed, but it seems rational choice citalopram in elderly depressed patients, regardless of whether they still suffer from dementia. |
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